sketchR

sketchR provides an R interface for subsampling and sketching algorithms implemented in python packages, with diagnostic plots to evaluate subsampling quality.

Key Features:

• geosketch interface: Provides access to the geosketch python package for geometric sketching of single-cell data.
• scSampler interface: Provides access to the scSampler python package for subsampling single-cell data.
• Diagnostic plots: Generates visualizations to evaluate and assess subsampling results.

Scientific Applications:

• Single-cell data subsampling: Enables scalable downsampling of large single-cell datasets while preserving biological structure through python-implemented sketching algorithms.
• Subsampling evaluation: Supports quality assessment of subsampling approaches via dedicated diagnostic plotting functionality.

Methodology:

sketchR wraps python subsampling algorithms for use in R, interfacing with geosketch and scSampler packages.