Spaniel

Spaniel includes tools to aid the quality control and analysis of Spatial Transcriptomics data.

Key Features:

• Data Import: Spaniel imports data from either the original Spatial Transcriptomics system or 10X Visium technology.
• Object Creation: The package contains functions to create a SingleCellExperiment Seurat object.
• Image Loading: Spaniel provides a method of loading a histological image into R.
• Spatial Visualization: The spanielPlot function visualizes metrics contained within the S4 object overlaid onto the image of the tissue.

Scientific Applications:

• Spatial Transcriptomics Quality Control: Spaniel aids quality control of Spatial Transcriptomics data.
• Spatial Transcriptomics Analysis: Spaniel supports analysis workflows for Spatial Transcriptomics data from the original Spatial Transcriptomics system or 10X Visium technology.

Methodology:

Spaniel imports data and creates SingleCellExperiment Seurat objects, loads histological images into R, and overlays S4 object metrics onto tissue images using spanielPlot.