SpatialDecon

SpatialDecon estimates abundance of mixed cell types within each observation using spatial or bulk gene expression data.

Key Features:

• Cell Type Deconvolution: Estimates abundance of mixed cell types within each observation from spatial or bulk gene expression data.
• Platform Compatibility: Designed for use with the NanoString GeoMx platform, but applicable to any gene expression data.

Scientific Applications:

• Spatial Transcriptomics Analysis: Enables quantification of cell types in spatial transcriptomic data.
• Bulk Gene Expression Deconvolution: Applicable to bulk gene expression data for mixed cell type estimation.

Methodology:

Based on "Advances in mixed cell deconvolution enable quantification of cell types in spatial transcriptomic data", Danaher (2022).