StructuralVariantAnnotation

StructuralVariantAnnotation provides a framework for analysis of structural variants within the Bioconductor ecosystem.

Key Features:

• VCF Parsing: The package contains functions for parsing VCFs from a number of popular callers.
• Breakpoint Handling: The package contains functions for dealing with breakpoints involving two separate genomic loci encoded as GRanges objects.
• Structural Variant Helper Functions: The package contains useful helper functions for dealing with structural variants in VCF format.

Scientific Applications:

• Structural Variant Analysis: The package enables analysis of structural variants within the Bioconductor ecosystem.

Methodology:

The package parses structural variant data from VCF format and represents breakpoints as GRanges objects.