SubCellBarCode

SubCellBarCode robustly classifies proteins into corresponding subcellular localization using mass spectrometry-based spatial proteomics data.

Key Features:

• Protein Classification: Robustly classifies proteins into their corresponding subcellular localizations based on mass spectrometry data.
• Visualization: Provides functionality for visualizing the mapped whole human spatial proteome.
• Integrated Workflow: Implements a complete workflow for spatial proteomics analysis from data processing to localization mapping.

Scientific Applications:

• Spatial Proteomics Mapping: Enables proteome-wide mapping of protein subcellular localization in human cells.
• Subcellular Localization Studies: Supports research on protein distribution across different cellular compartments.

Methodology:

Mass spectrometry-based spatial proteomics data are processed to classify proteins into subcellular localizations, building on the approach described by Orre et al. 2019 in Molecular Cell.