tidyCoverage

tidyCoverage enables tidy manipulation of collections of genomic tracks and features for extraction, aggregation, and visualization of genomic coverage over individual or thousands of genomic loci.

Key Features:

• Tidy data manipulation: Uses tidySummarizedExperiment methods for intuitive investigation of genomic track collections.
• Data structures: Defines CoverageExperiment and AggregatedCoverage classes, directly extending the SummarizedExperiment fundamental class.
• Coverage extraction: Facilitates extraction of genomic coverage track data across individual or multiple sets of thousands of genomic loci.
• Coverage aggregation: Supports aggregation of coverage profiles over sets of genomic loci.
• Visualization: Enables rapid visualization of track coverage at individual genomic loci or aggregated coverage profiles.
• Bioconductor integration: Seamlessly combines with the existing Bioconductor ecosystem for genome-wide track data integration.

Scientific Applications:

• Epigenomic analysis workflows: Accelerates integration of genome-wide track data in epigenomic analysis workflows.
• Genomic locus investigation: Supports exploration of genome-wide data across individual or multiple sets of thousands of genomic loci.
• Coverage profile analysis: Enables investigation of track coverage patterns at individual or aggregated genomic regions.

Methodology:

tidyCoverage relies on tidySummarizedExperiment methods and defines CoverageExperiment and AggregatedCoverage classes extending SummarizedExperiment.