TPP
TPP analyzes thermal proteome profiling experiments with varying temperatures or compound concentrations.
Key Features:
- Temperature Range (TR) Analysis: Supports analysis of experiments with varying temperatures.
- Compound Concentration Range (CCR) Analysis: Supports analysis of experiments with varying compound concentrations.
Scientific Applications:
- Thermal Proteome Profiling: Enables analysis of protein thermal stability and ligand-induced protein stabilization across temperature or compound concentration gradients.
Methodology:
Computational methods for analyzing thermal proteome profiling experiments are implemented; specific algorithmic details are not stated in the sources.
Collections
Details
- License:
- Artistic-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Mac, Windows
- Programming Languages:
- R
- Added:
- 9/1/2026
- Last Updated:
- 9/20/2026
Operations
Publications
DOI: 10.18129/B9.bioc.TPP
Documentation
User manual
https://bioconductor.org/packages/TPP