velociraptor

Velociraptor provides Bioconductor-friendly wrappers for RNA velocity calculations in single-cell RNA-seq data.

Key Features:

• Conda Environment Management: The package uses the basilisk package to manage Conda environments for running velocity methods.
• Data Structure Conversion: The package uses the zellkonverter package to convert data structures between SingleCellExperiment (R) and AnnData (Python).
• SingleCellExperiment Integration: The information produced by the velocity methods is stored in the various components of the SingleCellExperiment class.

Scientific Applications:

• Single-Cell RNA Velocity Analysis: Enables RNA velocity calculations in single-cell RNA-seq data within the Bioconductor ecosystem.

Methodology:

The package wraps RNA velocity methods by managing Conda environments with basilisk, converting between SingleCellExperiment and AnnData formats with zellkonverter, and storing velocity results in SingleCellExperiment components.