bioDist
bioDist computes distance measures for high-throughput genomic data to quantify similarity and dissimilarity for genomics and molecular biology analyses.
Key Features:
- Distance measures: Computes various distance measures used in genomics and molecular biology analyses.
- R implementation: Implemented in the R programming language for statistical analysis and integration with R data structures.
- Bioconductor integration: Integrates with the Bioconductor project and its packages to interoperate with other genomic analysis tools.
- High-throughput data support: Operates on high-throughput genomic datasets to derive similarity and dissimilarity metrics.
Scientific Applications:
- Comparative Genomics: Facilitates comparison of genetic datasets across organisms using computed distance measures.
- Phylogenetic Analysis: Assists in constructing phylogenetic trees by providing evolutionary distance estimates.
- Population Genetics: Enables analysis of genetic variation within and between populations through distance metrics.
Methodology:
Computes distance measures using statistical techniques implemented in R, allowing application of custom algorithms or pre-existing R functions.
Topics
Collections
Details
- License:
- Artistic-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/24/2024
Operations
Data Inputs & Outputs
Residue distance calculation
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.