biojs-vis-gprofiler

biojs-vis-gprofiler visualizes Gene Ontology (GO) enrichment results retrieved from g:Profiler as string clouds to aid interpretation of functional enrichment analyses.

Key Features:

• Integration with g:Profiler: Queries g:Profiler to retrieve enriched GO terms and access associated biological databases for functional enrichment analysis.
• String cloud visualization: Renders enriched GO terms as string clouds where term size and prominence reflect significance or relevance.

Scientific Applications:

• Functional Annotation: Annotates genes or proteins by reporting enriched GO terms linked to input gene lists.
• Hypothesis Generation: Highlights overrepresented GO terms to suggest biological processes, molecular functions, or cellular components for follow-up investigation.
• Data Interpretation and Communication: Summarizes enrichment results visually to facilitate interpretation and reporting of functional enrichment analyses.

Methodology:

Queries g:Profiler with input gene lists to identify statistically significant GO terms, then processes those terms and displays them as string clouds with term prominence corresponding to significance.