biojs-vis-inchlib
biojs-vis-inchlib visualizes biological datasets as cluster heatmaps to reveal sample- and feature-level patterns in gene expression, proteomics, metabolomics, and comparative genomics.
Key Features:
- Cluster Heatmap Generation: Generates cluster heatmaps that represent expression levels or presence/absence of features across multiple samples or conditions.
- Hierarchical Clustering: Organizes data into clusters using hierarchical clustering algorithms and similarity measures.
- Color Gradient Encoding: Encodes intensity or presence of specific biological features using color gradients in the heatmap.
Scientific Applications:
- Gene Expression Analysis: Visualizes gene expression data to identify clusters of genes with similar expression patterns across conditions.
- Proteomics and Metabolomics: Visualizes proteomic and metabolomic datasets to aid identification of biomarkers or pathway-level patterns.
- Comparative Genomics: Clusters genomic features to compare genetic variation across species or populations.
- Data Exploration: Summarizes large biological datasets visually to support exploratory analysis and hypothesis generation.
- Pattern Recognition: Highlights patterns and anomalies within complex biological data through clustered heatmap representation.
Methodology:
Hierarchical clustering algorithms organize data into clusters based on similarity measures, and resulting heatmaps use color gradients to represent intensity or presence of specific biological features.
Topics
Details
- Tool Type:
- library
- Operating Systems:
- Linux, Mac
- Programming Languages:
- JavaScript
- Added:
- 1/22/2015
- Last Updated:
- 12/10/2018
Operations
Data Inputs & Outputs
Heat map generation
Outputs
Publications
Yachdav G, Goldberg T, Wilzbach S, Dao D, Shih I, Choudhary S, Crouch S, Franz M, García A, García LJ, Grüning BA, Inupakutika D, Sillitoe I, Thanki AS, Vieira B, Villaveces JM, Schneider MV, Lewis S, Pettifer S, Rost B, Corpas M. Anatomy of BioJS, an open source community for the life sciences. eLife. 2015;4. doi:10.7554/elife.07009. PMID:26153621. PMCID:PMC4495654.