biojs-vis-sam

biojs-vis-sam visualizes Sequence Alignment/Map (SAM) format data to display read alignments and support interpretation of sequence alignment results.


Key Features:

  • SAM format visualization: Renders Sequence Alignment/Map (SAM) files to display read alignments.
  • Alignment representation: Transforms raw alignment data into visual representations to facilitate interpretation of complex alignment patterns.
  • Workflow integration: Integrates with existing bioinformatics workflows to incorporate SAM visualizations without extensive preprocessing or conversion.

Scientific Applications:

  • Data interpretation: Aids interpretation of sequence alignments by providing visual views of mapped reads and alignment features.
  • Comparative genomics: Supports examination of alignment differences across genomes or samples for comparative analyses.
  • Variant analysis: Assists inspection of alignments at loci of interest for variant validation and contextual assessment.
  • Transcriptome studies: Enables visualization of read alignments relevant to transcript structure and expression analyses.

Methodology:

Leverages the BioJS platform to render SAM format data for visualization and integrates with existing bioinformatics workflows without requiring extensive preprocessing or conversion.

Topics

Details

Tool Type:
library
Operating Systems:
Linux, Mac
Programming Languages:
JavaScript
Added:
1/22/2015
Last Updated:
11/25/2024

Operations

Publications

Yachdav G, Goldberg T, Wilzbach S, Dao D, Shih I, Choudhary S, Crouch S, Franz M, García A, García LJ, Grüning BA, Inupakutika D, Sillitoe I, Thanki AS, Vieira B, Villaveces JM, Schneider MV, Lewis S, Pettifer S, Rost B, Corpas M. Anatomy of BioJS, an open source community for the life sciences. eLife. 2015;4. doi:10.7554/elife.07009. PMID:26153621. PMCID:PMC4495654.

PMID: 26153621
PMCID: PMC4495654
Funding: - Engineering and Physical Sciences Research Council (EPSRC): EP/H043160/1

Documentation