Biologically motivated normalization techniques

The tool is designed to perform normalization at the image-level. This normalization method aims to reduce the variability in the intensity values of the Magnetic Resonance (MR) prostate images due to different scanners, acquisition protocols and conditions, based on the intensity values of specific tissues. This tool implements three biologically-motivated intensity normalization techniques: (1) The fat-based normalization method, (2) The muscle-based normalization method, and (3) The single tissue (fat or muscle) piece-wise normalization method.