BioMaster

BioMaster integrates and augments metadata for 47,934 BioBrick parts from the iGEM Registry to support synthetic biology research and genetic circuit engineering.


Key Features:

  • Collection: Aggregates 47,934 BioBrick items sourced from the iGEM Registry.
  • Database integration: Consolidates detailed information from ten distinct external databases.
  • Metadata augmentation: Enriches and standardizes metadata associated with BioBrick parts.
  • Functional annotation: Provides information on part functions, activities, and interactions.
  • Literature linkage: Links BioBrick entries to related scientific literature.
  • Analytical support: Enables retrieval and analysis of part information to inform design decisions in genetic circuit engineering.

Scientific Applications:

  • Synthetic biology research: Supports engineering and reconfiguration of biological systems using standardized BioBrick parts.
  • Genetic circuit engineering: Informs design and optimization of genetic circuits through enriched part metadata.
  • Part and device development: Facilitates development of new biological parts, devices, and systems via consolidated annotations.
  • Interaction and function inference: Enables mapping of part interactions and literature-informed functional interpretations.

Methodology:

Aggregates 47,934 BioBrick entries from the iGEM Registry and consolidates data from ten distinct databases to augment metadata and annotate functions, activities, interactions, and related scientific literature.

Topics

Details

Tool Type:
web application
Added:
3/19/2021
Last Updated:
3/19/2021

Operations

Publications

Wang B, Yang H, Sun J, Dou C, Huang J, Guo F. BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts. Frontiers in Microbiology. 2021;12. doi:10.3389/fmicb.2021.593979. PMID:33552037. PMCID:PMC7858672.