BiomeHorizon

BiomeHorizon visualizes longitudinal microbiome compositional dynamics using horizon plots to display relative and absolute changes in microbial taxa across subjects.

Key Features:

• Horizon Plot Visualization: Uses horizon plots to display proportional and absolute changes in microbial taxa abundances over time.
• Longitudinal Compositional Data Analysis: Handles longitudinal compositional microbiome data to track community dynamics across time points.
• Multi-taxa and Multi-subject Comparison: Displays multiple taxa across multiple subjects to facilitate comparison of temporal abundance patterns and inter-individual variability.
• R Package Implementation: Implemented as an R package for analysis and visualization of microbiome time-series data.

Scientific Applications:

• Microbiome Research: Analyzing temporal changes in microbial community composition in longitudinal studies.
• Comparative Studies: Comparing taxa abundance trajectories across subjects to identify common trends and inter-individual differences.

Methodology:

Employs horizon plots to visualize longitudinal compositional microbiome time-series data, representing both relative and absolute changes in taxa abundance across subjects; implemented as an R package.