BioSunMS

BioSunMS integrates patient metadata with mass spectrometry-derived peptide profiles to enable statistical analysis and biomarker discovery from MALDI-TOF MS and SELDI-TOF MS data.


Key Features:

  • Integrated Data Management: Manages patient information alongside mass spectrometry (MS) data to enable correlation of clinical metadata and peptide profiles.
  • Statistical Analysis of Peptide Profiles: Performs statistical comparisons of serum peptide profiles obtained via MALDI-TOF MS and SELDI-TOF MS.
  • Plug-In Architecture: Employs a plug-in-based architecture that permits extension or modification of analytical functionalities without recompiling the application.

Scientific Applications:

  • Early Diagnosis: Uses comparative analysis of peptide profiles to support identification of signatures indicative of early-stage disease.
  • Personalized Medicine: Correlates individual patient metadata with peptide patterns to inform tailored treatment strategies.
  • Biomarker Discovery: Facilitates identification of candidate peptide biomarkers through comprehensive statistical analysis of MALDI-TOF MS and SELDI-TOF MS data.

Methodology:

Performs statistical comparisons of serum peptide profiles derived from MALDI-TOF MS and SELDI-TOF MS, integrates patient metadata with MS data, and supports extension of analytical methods via a plug-in architecture.

Topics

Collections

Details

License:
GPL-1.0
Cost:
Free of charge
Tool Type:
plugin
Added:
3/6/2018
Last Updated:
11/25/2024

Operations

Publications

Cao Y, Wang N, Ying X, Li A, Wang H, Zhang X, Li W. BioSunMS: a plug-in-based software for the management of patients information and the analysis of peptide profiles from mass spectrometry. BMC Medical Informatics and Decision Making. 2009;9(1). doi:10.1186/1472-6947-9-13. PMID:19220920. PMCID:PMC2654546.

Documentation

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