BioWord

BioWord provides sequence manipulation and analysis functions within Microsoft Word 2007 and 2010 for editing and analyzing DNA and protein sequences, motif discovery, pair-wise alignment, and FASTA formatting.

Key Features:

• Sequence transformations: Performs reverse-complement operations and translates nucleotide or protein sequences.
• File format handling: Formats sequence data in FASTA format.
• Motif analysis: Implements dyad search, motif discovery, and consensus logo generation.
• Alignment: Provides pair-wise alignment functionality.
• Implementation and extensibility: Implemented in Visual Basic for Applications (VBA) as an object-oriented, open-source project that supports customization and extension of functionality.

Scientific Applications:

• Genetics: Manipulation and formatting of DNA sequences, reverse-complementation, and sequence translation for genetic analyses.
• Molecular biology: Motif discovery and consensus logo generation for identifying regulatory elements and protein features.
• Evolutionary studies: Pair-wise alignment and sequence comparisons for evolutionary and comparative analyses.

Methodology:

Implements reverse-complementation, sequence translation, FASTA formatting, dyad search, motif discovery, consensus logo generation, and pair-wise alignment in Visual Basic for Applications (VBA).