BURRITO

BURRITO integrates taxonomic and functional profiles to visualize and analyze co-variation between microbial taxa and gene functions in microbiome multi-omic and metagenomic datasets.

Key Features:

• Taxon–Function Integration: Integrates paired taxonomic and functional information to attribute gene functions to contributing microbial taxa across samples.
• Profile Visualization: Visualizes taxonomic groups and gene categories across multiple samples to display composition and relative abundance patterns.
• Dynamic Relationship Highlighting: Identifies and highlights relationships between taxa and functions to reveal contributors to functional categories across samples.
• Data Input Flexibility: Accepts multiple input formats for taxonomic and metagenomic data and accommodates data from diverse sequencing technologies.
• Adjustable Granularity: Allows aggregation or disaggregation of taxonomic and functional categories to explore patterns at different levels of resolution.

Scientific Applications:

• Exploratory Taxon–Function Analysis: Enables analysis of how microbial community composition relates to functional potential across samples.
• Ecological and Metabolic Studies: Supports investigations of ecological interactions and microbial metabolism by linking taxa to gene functions.
• Environmental Impact Assessment: Facilitates assessment of how environmental changes correlate with shifts in taxa-associated functional profiles.

Methodology:

Integrates paired taxonomic and functional datasets and applies advanced visualization techniques to represent and capture co-variation between microbial taxa and associated gene functions.