CaeNDR

CaeNDR provides curated whole-genome sequence data, annotated variants, and genome-wide association mapping resources for quantitative genetics and comparative genomics across the Caenorhabditis species C. elegans, C. briggsae, and C. tropicalis.

Key Features:

• Comprehensive Databases: Hosts continually updated strain collections, whole-genome sequence data, and annotated variants for multiple Caenorhabditis species.
• Natural Variation Exploration Tools: Provides interactive tools to explore natural genetic variation and identify variants contributing to phenotypic diversity.
• Genome-Wide Association (GWA) Mapping Portal: Includes a GWA mapping portal tailored for Caenorhabditis to link genetic variants to phenotypic traits across strains and species.

Scientific Applications:

• Quantitative Genetics: Identify genetic loci and alleles underlying quantitative trait variation within and among Caenorhabditis species.
• Genome-Wide Association Studies: Perform GWAS to associate specific variants with phenotypic traits across strains and species.
• Comparative Genomics and Evolutionary Biology: Compare natural genetic variation across C. elegans, C. briggsae, and C. tropicalis to study evolutionary processes.
• Functional Analysis of Natural Variation: Investigate the functional implications of annotated variants for phenotype and trait evolution.

Methodology:

Genome-wide association (GWA) mapping and provision of annotated variants derived from whole-genome sequence data.