CamRegBase

CamRegBase provides a centralized repository of gene expression and regulatory information for Camelina (Brassicaceae), enabling analysis of transcription factors, co-expression, lipid-associated genes, and genome-wide orthologs with Arabidopsis thaliana to support functional genomics and biofuel-related research.


Key Features:

  • Gene Expression Data: Extensive Camelina-specific gene expression profiles across conditions and developmental stages.
  • Co-expression Analysis: Support for identifying groups of genes with correlated expression patterns to infer functional associations.
  • Transcription Factor Information: Cataloged transcription factors for investigating gene regulatory networks and regulation of metabolic pathways.
  • Lipid-Associated Genes: Detailed information on genes involved in lipid metabolism relevant to oil production and biofuel traits.
  • Genome-Wide Orthologs: Orthologous gene mappings between Camelina and Arabidopsis thaliana for comparative functional inference.

Scientific Applications:

  • Functional Genomics Studies: Analysis of genes and regulatory networks underlying lipid biosynthesis and other pathways in Camelina.
  • Genetic Engineering Efforts: Identification of candidate genes and regulatory targets for modifying oil yield or composition.
  • Comparative Genomics Research: Leveraging Arabidopsis thaliana orthologs to accelerate annotation and discovery of conserved regulatory mechanisms.

Methodology:

Compilation, curation, and integration of community-generated Camelina gene expression datasets.

Topics

Details

Added:
1/18/2021
Last Updated:
2/6/2021

Operations

Publications

Gomez-Cano F, Carey L, Lucas K, García Navarrete T, Mukundi E, Lundback S, Schnell D, Grotewold E. CamRegBase: a gene regulation database for the biofuel crop, <i>Camelina sativa</i>. Database. 2020;2020. doi:10.1093/database/baaa075. PMID:33306801. PMCID:PMC7731927.

PMID: 33306801
PMCID: PMC7731927
Funding: - Division of Graduate Education: DGE-1828149 - Basic Energy Sciences: DE-SC0018269