CamRegBase
CamRegBase provides a centralized repository of gene expression and regulatory information for Camelina (Brassicaceae), enabling analysis of transcription factors, co-expression, lipid-associated genes, and genome-wide orthologs with Arabidopsis thaliana to support functional genomics and biofuel-related research.
Key Features:
- Gene Expression Data: Extensive Camelina-specific gene expression profiles across conditions and developmental stages.
- Co-expression Analysis: Support for identifying groups of genes with correlated expression patterns to infer functional associations.
- Transcription Factor Information: Cataloged transcription factors for investigating gene regulatory networks and regulation of metabolic pathways.
- Lipid-Associated Genes: Detailed information on genes involved in lipid metabolism relevant to oil production and biofuel traits.
- Genome-Wide Orthologs: Orthologous gene mappings between Camelina and Arabidopsis thaliana for comparative functional inference.
Scientific Applications:
- Functional Genomics Studies: Analysis of genes and regulatory networks underlying lipid biosynthesis and other pathways in Camelina.
- Genetic Engineering Efforts: Identification of candidate genes and regulatory targets for modifying oil yield or composition.
- Comparative Genomics Research: Leveraging Arabidopsis thaliana orthologs to accelerate annotation and discovery of conserved regulatory mechanisms.
Methodology:
Compilation, curation, and integration of community-generated Camelina gene expression datasets.
Topics
Details
- Added:
- 1/18/2021
- Last Updated:
- 2/6/2021
Operations
Publications
Gomez-Cano F, Carey L, Lucas K, García Navarrete T, Mukundi E, Lundback S, Schnell D, Grotewold E. CamRegBase: a gene regulation database for the biofuel crop, <i>Camelina sativa</i>. Database. 2020;2020. doi:10.1093/database/baaa075. PMID:33306801. PMCID:PMC7731927.
PMID: 33306801
PMCID: PMC7731927
Funding: - Division of Graduate Education: DGE-1828149
- Basic Energy Sciences: DE-SC0018269