CancerSubtypes

CancerSubtypes identifies cancer molecular subtypes by integrating and standardizing computational biology methods for analysis of high-throughput genomic datasets within the R/Bioconductor ecosystem.


Key Features:

  • Integration with Bioconductor: Operates within the Bioconductor project and leverages the R environment and an ecosystem of 934 interoperable Bioconductor packages.
  • Standardized framework: Provides a standardized approach to cancer subtype analysis to support consistency and reproducibility across studies.
  • Interoperability: Facilitates integration with other bioinformatics tools and workflows via Bioconductor package interoperability.
  • High-throughput data analysis: Processes high-throughput genomic datasets for subtype discovery.
  • Community-driven development: Benefits from contributions and updates from the Bioconductor developer community.

Scientific Applications:

  • Cancer subtype identification: Identifies distinct molecular cancer subtypes from genomic datasets to inform studies of tumor heterogeneity and targeted therapies.
  • Interdisciplinary research: Provides a common computational platform for researchers in genomics, bioinformatics, and clinical studies to analyze cancer subtypes.

Methodology:

Integrates and standardizes computational biology methods, runs within R/Bioconductor using Bioconductor packages, and processes high-throughput genomic datasets for subtype analysis.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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