Catana

Catana facilitates rational design and manipulation of proteins, DNA, and organic nanostructures for molecular engineering and nanotechnology applications.

Key Features:

• AI-driven structure prediction: Predicts protein structures from amino acid sequences using AI-based prediction tools.
• Recombinant fusion protein design: Supports design and modification of recombinant fusion proteins.
• DNA origami and DNA nanostructure manipulation: Enables design and manipulation of DNA origami and complex DNA nanostructures.
• Unified Nanotechnology Format (UNF) and coarse-grained model: Employs a coarse-grained data model conforming to the Unified Nanotechnology Format (UNF) for interoperability with molecular design tools.
• Export for molecular dynamics simulations: Exports designs for in silico evaluation via molecular dynamics simulations.

Scientific Applications:

• Protein engineering: Enables generation and evaluation of engineered proteins and recombinant fusions, including structure prediction from sequences.
• DNA nanotechnology: Supports design and testing of DNA origami and complex DNA nanostructures for nanotechnological applications.
• Biotechnology and medicine: Facilitates molecular design workflows relevant to biotechnology and medical research.
• In silico evaluation: Supports preparation of models and data for molecular dynamics-based in silico assessment of molecular designs.

Methodology:

Integrates advanced computational techniques, including compatibility with AI-based protein structure prediction from amino acid sequences and a coarse-grained data model conforming to the Unified Nanotechnology Format (UNF).