CCPlotR

CCPlotR visualizes predicted cell-cell interactions from single-cell gene expression data to represent cellular communication networks.


Key Features:

  • Input Requirements: Accepts a table of predicted interactions derived from single-cell gene expression analyses.
  • Compatibility: Operates with outputs from computational tools that predict cell-cell interactions.
  • Visualization Capabilities: Provides heatmaps, dotplots, circos plots, and network diagrams to represent interaction matrices, per-interaction metrics, circular relationship layouts, and connection networks.

Scientific Applications:

  • Systems biology: Facilitates interpretation of intercellular communication networks in systems biology studies.
  • Immunology: Supports analysis of cell-cell communication relevant to immunology research.
  • Developmental biology: Supports analysis of cell-cell interactions in developmental biology contexts.

Methodology:

Visualizes predicted interaction tables derived from single-cell gene expression analyses using heatmaps, dotplots, circos plots, and network diagrams.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
4/8/2024
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Publications

Ennis S, Ó Broin P, Szegezdi E. CCPlotR: an R package for the visualization of cell–cell interactions. Bioinformatics Advances. 2023;3(1). doi:10.1093/bioadv/vbad130. PMID:37767186. PMCID:PMC10521630.

PMID: 37767186
Funding: - Science Foundation Ireland: 18/CRT/6214

Links