CellML

CellML defines an XML-based language for describing and exchanging mathematical models of physiological systems, using MathML to encode the underlying mathematics.

Key Features:

• XML-based format: CellML 2.0 represents model structure and content using XML syntax.
• MathML integration: MathML is used to define the mathematical equations and expressions within models.
• Modular component architecture: Models are composed of reusable components assembled into networks.
• Component encapsulation: Each component encapsulates variables and equations that establish relationships and dynamics.
• Model import and composition: Models can import other CellML models to construct larger systems from sub-models.
• Normative specification and interoperability: A normative specification prescribes syntax and usage rules to ensure consistency and interoperability across software tools.

Scientific Applications:

• Model description and exchange: Representing and exchanging mathematical models of physiological systems.
• Model composition: Building comprehensive system models by importing and combining simpler sub-models.
• Dynamic physiological modeling: Capturing relationships between variables and equations to model dynamic physiological interactions.
• Interoperability: Enabling consistent model interpretation and use across tools that consume CellML syntax.

Methodology:

Models are encoded in XML and use MathML for mathematical definitions; they organize behavior into modular components that encapsulate variables and equations, support importing other CellML models, and are governed by a normative specification defining syntax and usage for interoperability.