CellRemorph
CellRemorph converts and manipulates astrocyte morphologies in Blender to enable simulation and analysis of astrocyte structure and function.
Key Features:
- Transformation Capabilities: Converts polygonal surface meshes to adjustable surface point clouds and vice versa to provide alternative morphology representations for analysis and simulation.
- Selection Precision: Enables precise selection and extraction of nanoprocesses within astrocyte structures for targeted morphological analysis.
- Segmentation Functionality: Slices morphologies into segments with equal surface areas or equal volumes to create uniform sections for comparative studies.
Scientific Applications:
- Computational modeling of astrocyte morphology: Builds models that capture intricate morphological details of astrocytes from existing morphological data.
- Simulation of astrocyte function: Prepares morphology representations tailored to simulations probing astrocyte roles in health and disease.
- Comparative morphological analysis: Produces uniformly segmented models to facilitate comparative studies and detailed simulations.
- Targeted nanoprocess studies: Isolates nanoprocesses for region-specific structural and functional analyses.
Methodology:
Computational steps include conversion between polygonal surface meshes and adjustable surface point clouds, selection and extraction of nanoprocesses, and slicing morphologies into equal surface-area or equal-volume segments.
Topics
Details
- License:
- GPL-3.0
- Cost:
- Free of charge
- Tool Type:
- desktop application
- Operating Systems:
- Mac, Linux, Windows
- Added:
- 1/1/2024
- Last Updated:
- 11/24/2024
Operations
Publications
Keto L, Manninen T. CellRemorph: A Toolkit for Transforming, Selecting, and Slicing 3D Cell Structures on the Road to Morphologically Detailed Astrocyte Simulations. Neuroinformatics. 2023;21(3):483-500. doi:10.1007/s12021-023-09627-5. PMID:37133688. PMCID:PMC10406679.