cfOmics

cfOmics integrates multi-omics data derived from liquid biopsy samples to support analysis of cell-free biomarkers across multiple diseases.

Key Features:

• Cell-Free Multi-Omics Integration: Aggregates circulating free DNA (cfDNA), cell-free RNA (cfRNA) sequencing data, and proteomic and metabolomic profiles obtained by mass spectrometry.
• Disease-Centered Dataset Collection: Contains 17 data types across 13 specimen types representing 11,345 samples spanning 69 disease conditions.
• Cell-Free Biomarker Repository: Compiles reported candidate biomarkers derived from cell-free multi-omics studies.
• Genomic and Correlation Analysis: Enables exploration of gene, microbial, and DNA end-motif relationships and supports visualization through Integrative Genomics Viewer.

Scientific Applications:

• Liquid Biopsy Biomarker Discovery: Identifies and evaluates circulating biomarkers for disease detection and monitoring.
• Multi-Omics Disease Research: Investigates relationships among cfDNA, cfRNA, proteomic, and metabolomic profiles across disease conditions.

Methodology:

cfOmics integrates sequencing-derived cfDNA and cfRNA data with mass spectrometry–based proteomic and metabolomic datasets and provides genomic visualization and correlation analysis of genes, microbes, and DNA end motifs.