CG-DIVA

CG-DIVA evaluates the performance of continuous glucose monitoring (CGM) systems by characterizing glucose measurement deviations and variability relative to a comparison method.

Key Features:

• Deviation Interval Characterization: Quantifies expected ranges of CGM measurement deviations from a reference comparison method across glucose concentration ranges.
• Sensor Variability Assessment: Measures both within-sensor and between-sensor variability to evaluate CGM measurement consistency.
• Error Distribution Analysis: Identifies the incidence and magnitude of large measurement errors relevant to clinical interpretation.

Scientific Applications:

• CGM Accuracy Evaluation: Assesses the analytical accuracy of continuous glucose monitoring systems in accordance with performance requirements for integrated CGM devices.
• Comparative Device Analysis: Enables standardized comparison of performance metrics across different CGM systems.

Methodology:

CG-DIVA applies statistical tolerance interval analysis to CGM measurements relative to a comparison method to quantify deviation ranges and evaluate within-sensor and between-sensor variability.