Candida genome database CGD

Candida Genome Database CGD provides curated genomic sequences, gene and protein annotations, and functional data for Candida species, particularly the human pathogen Candida albicans, to support genomic and functional analysis.

Key Features:

• Curated Genomic and Protein Annotations: Integrates genomic sequences and manually curated functional annotations for genes and proteins from Candida albicans and related Candida species.
• Orthology Relationship Mapping: Links orthologous genes across species such as Candida albicans and Candida glabrata to support comparative genomics and Gene Ontology (GO) annotation inference.
• Metabolic Pathway Visualization: Provides biochemical pathway representations for Candida metabolism and supports interpretation of experimental datasets within pathway contexts.
• Literature Mining with Textpresso: Enables full-text literature searches related to Candida biology using the Textpresso text-mining system.
• Protein Structural and Functional Data: Includes information on protein domains, structural characteristics, and physicochemical properties of Candida proteins.
• Strain Lineage and Bibliographic Data: Documents laboratory strain lineages and bibliographic references relevant to Candida research.

Scientific Applications:

• Candida Genomics and Functional Analysis: Supports investigation of gene function, protein properties, and genomic organization in pathogenic Candida species.
• Comparative Fungal Genomics: Enables cross-species analysis of orthologous genes and conserved biological processes among Candida species.

Methodology:

CGD integrates curated genomic sequences, orthology relationships, biochemical pathway data, protein annotations, and literature mining through the Textpresso system to support genomic and functional analyses of Candida species.