chopsticks
chopsticks performs large-scale single nucleotide polymorphism (SNP) association studies to identify genetic variants associated with traits and diseases.
Key Features:
- Scalability: Implements processing capabilities to handle extensive SNP datasets typical of large-scale genomic analyses.
- Bioconductor integration: Integrates with the Bioconductor ecosystem to enable interoperability with other Bioconductor packages and workflows.
- Object-oriented classes and methods: Provides classes and methods tailored to manage the complexity and scale of SNP association data within R.
Scientific Applications:
- Genomic research: Facilitates SNP association analyses to identify genetic markers linked to specific traits or diseases.
- Interdisciplinary research: Supports combining statistical programming in R with bioinformatics workflows for collaborative studies.
Methodology:
Implements classes and methods in the R statistical programming language and is distributed within the Bioconductor framework, following package standards including initial review and continuous automated testing.
Topics
Collections
Details
- License:
- GPL-3.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.