ChromoViz

ChromoViz visualizes multimodal genomic datasets, including microarray gene expression data, DNA copy number alterations, and non-expression genomic information, to support cross-species and cross-platform comparative genomic analyses.

Key Features:

• Multimodal Visualization: Supports visualization of microarray gene expression profiles, DNA copy number alterations, and non-expression genomic information together for integrated analysis.
• Cross-Species and Cross-Platform Comparisons: Enables comparative analyses across species and experimental platforms to identify conserved genetic elements and platform-specific biases.
• Integration with Public Databases: Incorporates non-expression genomic data sourced from public databases to combine expression data with additional genomic annotations.
• Chromosomal Visualization Format: Implements a chromosomal visualization format that decouples the data layer from the procedure layer for flexible representation of datasets on chromosomes.

Scientific Applications:

• Evolutionary Biology: Facilitates analysis of conserved genomic elements and divergence across species using integrated genomic data.
• Comparative Genomics: Supports identification of conserved genetic elements and platform-specific biases through cross-species and cross-platform comparisons.
• Multi-omic Integration: Enables joint visualization and comparison of expression, copy number, and other genomic annotations for multi-omic analyses.

Methodology:

Implemented as an R package that separates data processing from visualization and implements a chromosomal visualization format that decouples the data layer from the procedure layer.