CircularLogo

CircularLogo visualizes DNA and RNA sequence motifs using a circular sequence-logo layout that integrates intra-motif dependencies to represent position-specific nucleotide consensus and positional interactions.

Key Features:

• Circular Layout: Employs a circular design that depicts nucleotide stacks and represents intra-motif dependencies using linked arches.
• Visualization of Dependencies: Represents position-specific nucleotide consensus and diversity while illustrating pairwise positional dependencies within motifs.

Scientific Applications:

• HNF6 binding sites: Applied to visualization of HNF6 binding sites to reveal intra-motif dependencies.
• tRNA sequences: Applied to tRNA sequence analysis to reveal underlying biomolecular structure through dependency visualization.

Methodology:

Implemented in JavaScript and Python and built using the Django web framework.