Clone Mapper

Clone Mapper maps bacterial RNAi clone sequences to Caenorhabditis elegans genomic targets to verify bacterial clone identities and identify potential RNAi targets from clones producing double-stranded RNAs for genome-wide RNAi screens.

Key Features:

• Automated analysis pipeline: Performs automated analytical steps including verification of bacterial clone identities and identification of potential targets for RNAi experiments.
• Scalability: Processes large datasets from genome-wide RNAi screens involving numerous bacterial clones producing double-stranded RNAs.
• Accuracy and efficiency: Automates verification and target identification to reduce manual error and increase throughput of RNAi data analysis.

Scientific Applications:

• Genome-wide RNAi screens: Supports mapping of bacterial RNAi clones to C. elegans genomic targets and identification of candidate gene hits in large-scale screens.
• Functional genomics and gene function investigation: Enables discovery of biologically relevant genes through validated clone-to-target assignments from RNAi experiments.

Methodology:

Integration of automated analytical processes that systematically perform verification of bacterial clone identities and identification of potential RNAi targets.