CMR

CMR provides a central repository of sequence and annotation for complete public prokaryotic genomes to enable comparative microbial genomics and targeted data retrieval.

Key Features:

• Central Repository: Hosts an extensive collection of annotated complete prokaryotic genomes.
• Robust Annotation: Provides detailed, consistent annotation across hosted microbial genomes.
• Data Retrieval Options: Enables retrieval by protein properties (molecular weight, hydrophobicity), GC-content, functional roles, and taxonomy.
• Comparative Genomics Analyses: Includes pre-run homology searches and whole genome dot-plots for genome comparison.
• Batch Downloading: Supports batch downloading of datasets for large-scale analyses.
• Genome Traversal: Offers traversal across genomes using multiple data types to facilitate comparative queries.

Scientific Applications:

• Microbial Genomics: Enables analysis and annotation of prokaryotic genomes for basic genomic studies.
• Comparative Genomics: Facilitates identification of genetic similarities and differences among microbial species using homology searches and dot-plots.
• Taxonomy and Evolutionary Biology: Supports studies of microbial taxonomy and evolutionary relationships.
• Functional Genomics: Supports analysis of gene function and assignment of functional roles.
• Genetic Diversity and Genome Comparison: Enables exploration of genetic diversity across complete genomes.
• Biotechnology and Medicine: Provides resources for applied studies in biotechnology and medical microbiology.

Methodology:

Employs advanced comparative genomics tools including pre-run homology searches and whole genome dot-plots, with support for batch downloading and traversal across genomes using multiple data types.