Colora

Colora automates chromosome-scale de novo primary or phased genome assembly complete with organelles from Pacific Biosciences HiFi, Hi-C, and optionally Oxford Nanopore Technologies reads.

Key Features:

• Primary or Phased Assembly: Produces either primary or phased genome assemblies.
• Organelle Assembly: Generates complete organelle assemblies alongside nuclear genomes.
• Multi-Platform Input: Integrates Pacific Biosciences HiFi, Hi-C, and optionally Oxford Nanopore Technologies reads.
• Snakemake Framework: Implemented as an automated, portable workflow using Snakemake.

Scientific Applications:

• Reference Genome Generation: Creates reference genomes for biodiversity and conservation studies.
• De Novo Genome Assembly: Enables high-quality automated assembly for researchers generating new genomes.

Methodology:

Colora is implemented as a Snakemake workflow.