COMMODAR

COMMODAR extracts context-specific molecular relations from unstructured biomedical literature to produce structured representations of molecular interactions for computational biology and bioinformatics analyses.


Key Features:

  • Multimodal Representations: Combines biomedical domain knowledge with canonical linguistic information to augment features for relation extraction.
  • Machine Learning Framework: Employs a machine learning–based framework, including neural networks, to perform relation extraction from text.
  • Context-Specific Extraction: Focuses on extracting molecular relations that are specific to biological contexts rather than generic associations.
  • Large-Scale Literature Mining: Applied to 14 million PubMed abstracts and produced 9,214 context-specific molecular relations.

Scientific Applications:

  • Biological Network Construction: Provides context-specific molecular relations for building and refining biological interaction networks.
  • Literature-Scale Knowledge Extraction: Enables extraction of molecular relations from large corpora of biomedical texts for downstream computational analyses.

Methodology:

Multimodal representations combining biomedical domain knowledge and canonical linguistic information; machine learning–based relation extraction using neural networks; large-scale application to PubMed abstracts (14 million) yielding 9,214 extracted context-specific molecular relations.

Topics

Details

Tool Type:
command-line tool
Programming Languages:
Java, Python
Added:
1/18/2021
Last Updated:
2/17/2021

Operations

Publications

Lee J, Lee D, Lee KH. Literature mining for context-specific molecular relations using multimodal representations (COMMODAR). BMC Bioinformatics. 2020;21(S5). doi:10.1186/s12859-020-3396-y. PMID:33106154. PMCID:PMC7586695.

PMID: 33106154
PMCID: PMC7586695
Funding: - National Research Foundation of Korea: NRF-2012M3A9C4048758