Companion

Companion annotates parasite, fungi, and arthropod genomes using a reference-based method, enabling assessment of structural and functional annotation prior to database submission.

Key Features:

• Reference-based annotation: Annotates genomes using closely related reference genomes rather than de novo methods.
• Gene finding: Incorporates novel gene-finding methods for identifying correct gene sequences.
• Expanded reference coverage: Reference set includes genomes from fungi and arthropods relevant to human and animal health.
• Scalability: Efficient annotation of genomes up to 1 Gb in size.
• RNA annotation: Annotates non-coding RNA elements in addition to protein-coding genes.
• Quality assessment: Enables assessment of annotation output quality prior to submission.

Scientific Applications:

• Parasite genome annotation: Structural and functional annotation of parasite genome assemblies.
• Fungi genome annotation: Annotation of fungal genomes of interest for human and animal health.
• Arthropod genome annotation: Annotation of arthropod genomes relevant to human and animal health.
• Database submission preparation: Generation of annotated genome data suitable for submission to public databases.

Methodology:

Reference-based annotation method using a reference set of genomes; specific computational steps are not explicitly detailed in the sources.