Comparative genometrics CG database

Comparative genometrics CG database performs genometric analyses of complete chromosome sequences to characterize genomic structure and identify taxon-specific features across prokaryotes, plasmids, phages, viruses, and eukaryotic organelles.

Key Features:

• Genometric Analyses: Implements DNA Walk, cumulative GC skew analysis (guanine (G) and cytosine (C) distribution), and TA skew analysis (thymine (T) and adenine (A) distribution) for whole-chromosome characterization.
• Taxon-Specific Feature Detection: Identifies taxon-specific genomic features relevant to evolutionary relationships and functional genomics.
• Broad Applicability: Applies analyses to prokaryotic chromosomes, paradigm plasmids, phages, viruses, and eukaryotic organelles.

Scientific Applications:

• Comparative Genomics: Enables comparison of chromosome sequences to support evolutionary biology, phylogenetics, and studies of genetic diversity.
• Genomic Organization Studies: Facilitates identification of organizational principles and structural features such as replication origins via skew analyses and DNA Walks.
• Educational Resource: Provides real-data examples of genometric analyses for teaching genomic analysis concepts.

Methodology:

Applies biometric and genometric methods as described by Elston and Wilson, specifically using DNA Walk, cumulative GC skew (G vs C) and TA skew (T vs A) analyses to quantify whole-chromosome features.