Comprotein

Comprotein determines the primary structure of proteins by performing protein sequencing to identify amino acid sequences for genetic and molecular analyses.


Key Features:

  • Primary structure determination: Provides computational support to determine the primary structure of proteins.
  • Protein sequencing: Performs protein sequencing to establish the linear order of amino acids in polypeptide chains.
  • Amino acid resolution: Identifies amino acid sequences within protein chains for downstream functional and interaction studies.
  • Genetic information decoding: Leverages bioinformatics techniques to interpret gene-encoded information into amino acid sequence representations.

Scientific Applications:

  • Protein function and interaction analysis: Supports studies of protein function and molecular interactions based on primary sequence information.
  • Genetics: Aids genetic studies by linking gene sequences to their encoded amino acid sequences.
  • Molecular biology: Facilitates molecular biology investigations that require precise protein primary structure data.
  • Biochemistry: Enables biochemical analyses that depend on accurate amino acid sequence information.
  • Evolution and development (ontogeny): Contributes to evolutionary and developmental studies through comparison of protein primary structures.

Methodology:

Uses computational protein sequencing and bioinformatics techniques to sequence amino acids and decode information encoded within genes.

Details

Maturity:
Legacy
Programming Languages:
Fortran
Added:
9/25/2025
Last Updated:
9/25/2025

Operations

Data Inputs & Outputs

Publications

Dayhoff MO, Ledley RS. Comprotein. Proceedings of the December 4-6, 1962, fall joint computer conference on - AFIPS '62 (Fall). 1962. doi:10.1145/1461518.1461546.