Coronapp

Coronapp annotates and monitors mutations in SARS-CoV-2 genomes to support genomic surveillance and evolutionary analysis.

Key Features:

• Sequence annotation: Annotates uploaded SARS-CoV-2 genomic sequences to identify nucleotide and amino acid changes.
• Mutation highlighting and categorization: Identifies specific mutations and categorizes them by frequency, country, genomic position, and impact on protein sequences.
• Global visualization: Visualizes the worldwide distribution of SARS-CoV-2 mutations across regions.
• Temporal monitoring: Monitors the presence and frequency of mutations over time to track emerging variants.

Scientific Applications:

• Epidemiological studies: Tracks mutation frequencies and geographic distributions to inform analyses of viral spread.
• Evolutionary biology: Provides mutation and protein-impact data to support studies of SARS-CoV-2 evolution.
• Public health surveillance: Enables monitoring of emerging variants of concern through temporal and geographic mutation data.

Methodology:

Performs sequence annotation and mutation identification, categorizes mutations by frequency, country, genomic position, and protein-level impact, and generates global visualizations and temporal monitoring of mutations.