CORREP

CORREP estimates multivariate correlations and performs statistical inference for high-dimensional genomics and molecular biology data.


Key Features:

  • Multivariate Correlation Estimation: Estimates correlations across multiple variables simultaneously for high-dimensional datasets, including genes and proteins.
  • Statistical Inference: Provides robust statistical inference methods for hypothesis testing and validation of results from high-throughput genomic data.
  • Integration with Bioconductor and R: Integrates with the Bioconductor project and the R statistical programming environment for interoperability with other packages.
  • Open-Source Development: Distributed as open-source software to enable community contributions and transparency.
  • Formal Review and Automated Testing: Operates within Bioconductor's framework of formal initial review and continuous automated testing to ensure reliability.

Scientific Applications:

  • Genomics: Analyzes relationships among genes and genetic markers to investigate biological pathways and mechanisms.
  • Molecular Biology: Examines gene expression patterns and protein interactions to support biomarker discovery and therapeutic target research.

Methodology:

Uses multivariate analysis and advanced statistical techniques to handle high-dimensional genomics data.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads