COVID-19 Knowledge Graph
COVID-19 Knowledge Graph encodes cause-and-effect relationships from scientific literature about SARS-CoV-2 pathophysiology into a computable knowledge graph for computational reasoning and hypothesis generation.
Key Features:
- Multi-modal Knowledge Representation: Integrates diverse data types and sources to capture complex interactions within COVID-19 pathophysiology.
- Cause-and-Effect Network: Focuses on causal relationships to represent how biological processes and factors contribute to disease progression and outcomes.
- Computable Format: Provides a structured, machine-readable graph representation that enables computational analysis and large-scale hypothesis testing.
Scientific Applications:
- Research Facilitation: Centralizes formalized knowledge to support individual and collaborative research on COVID-19 pathophysiology.
- Data Exploration and Analysis: Enables large-scale computational exploration and analysis to identify novel connections and generate hypotheses about SARS-CoV-2 impacts.
Methodology:
Extracted knowledge from scientific publications and formalized it into a structured network of cause-and-effect relationships, then encoded the graph in multiple standard formats.
Topics
Collections
Details
- License:
- CC0-1.0
- Tool Type:
- library
- Programming Languages:
- Python
- Added:
- 1/18/2021
- Last Updated:
- 11/24/2024
Operations
Publications
Domingo-Fernández D, Baksi S, Schultz B, Gadiya Y, Karki R, Raschka T, Ebeling C, Hofmann-Apitius M, Kodamullil AT. COVID-19 Knowledge Graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology. Unknown Journal. 2020. doi:10.1101/2020.04.14.040667.
Domingo-Fernández D, Baksi S, Schultz B, Gadiya Y, Karki R, Raschka T, Ebeling C, Hofmann-Apitius M, Kodamullil AT. COVID-19 Knowledge Graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology. Bioinformatics. 2020;37(9):1332-1334. doi:10.1093/bioinformatics/btaa834. PMID:32976572. PMCID:PMC7558629.