cpgplot

cpgplot identifies and visualizes CpG islands in nucleotide sequences to support analysis of promoter regions and DNA methylation-related epigenetic regulation.


Key Features:

  • Identification of CpG Islands: Detects regions enriched in CpG dinucleotides (CpG islands) within DNA sequences, which often correlate with promoter elements.
  • Visualization Capabilities: Plots identified CpG islands within input nucleotide sequences to aid interpretation of genomic organization and regulatory context.
  • Integration with EMBOSS Suite: Operates within the EMBOSS suite and leverages EMBOSS components for analysis and plotting.

Scientific Applications:

  • Gene Regulation Studies: Maps CpG islands to investigate promoter-associated mechanisms of gene expression regulation.
  • Epigenetic Research: Supports analysis of DNA methylation-related patterns at CpG islands relevant to epigenetic control of gene expression.
  • Comparative Genomics: Enables comparison of CpG island distribution across sequences to identify conserved regulatory elements.

Methodology:

Analyzes nucleotide sequences to locate CpG-rich regions and leverages EMBOSS's C programming libraries for identification and plotting of CpG islands.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

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