cpgplot
cpgplot identifies and visualizes CpG islands in nucleotide sequences to support analysis of promoter regions and DNA methylation-related epigenetic regulation.
Key Features:
- Identification of CpG Islands: Detects regions enriched in CpG dinucleotides (CpG islands) within DNA sequences, which often correlate with promoter elements.
- Visualization Capabilities: Plots identified CpG islands within input nucleotide sequences to aid interpretation of genomic organization and regulatory context.
- Integration with EMBOSS Suite: Operates within the EMBOSS suite and leverages EMBOSS components for analysis and plotting.
Scientific Applications:
- Gene Regulation Studies: Maps CpG islands to investigate promoter-associated mechanisms of gene expression regulation.
- Epigenetic Research: Supports analysis of DNA methylation-related patterns at CpG islands relevant to epigenetic control of gene expression.
- Comparative Genomics: Enables comparison of CpG island distribution across sequences to identify conserved regulatory elements.
Methodology:
Analyzes nucleotide sequences to locate CpG-rich regions and leverages EMBOSS's C programming libraries for identification and plotting of CpG islands.
Topics
Collections
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C
- Added:
- 11/8/2015
- Last Updated:
- 12/10/2018
Operations
Publications
Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.
Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.
Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.
Documentation
Terms of use
http://emboss.open-bio.org/html/dev/ch01s01.htmlCitation instructions
http://emboss.open-bio.org/html/use/pr02s04.html