CPSS

CPSS analyzes small RNA sequencing data to detect and profile non-coding RNAs (ncRNAs), including long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), and to perform differential expression analysis across multiple samples and species.

Key Features:

• Expanded Species Support: Supports 48 species (expanded from 10 in the previous version) to broaden applicability across organisms.
• Enhanced ncRNA Detection Strategies: Implements improved methodologies for comprehensive identification and profiling of ncRNAs, including lncRNAs and circRNAs.
• Differential Expression Analysis: Identifies differentially expressed ncRNAs among multiple samples to enable comparative expression studies.
• Data Visualization: Produces detailed graphs and charts to visualize small RNA and ncRNA analysis results.

Scientific Applications:

• Non-coding RNA research: Detection and profiling of ncRNAs across species to support studies of ncRNA biology.
• Gene expression regulation: Analysis of ncRNA expression patterns relevant to regulation of gene expression.
• Disease mechanisms and biomarker discovery: Differential expression analysis to identify candidate biomarkers or therapeutic targets.
• Comparative and evolutionary studies: Multi-species support facilitates comparative analyses and evolutionary investigations of ncRNAs.

Methodology:

Implemented using PHP, Perl, and R.