CRIMSON

CRIMSON performs subject-specific hemodynamic analysis by enabling segmentation of vascular structures, construction of arterial and venous geometries, finite element mesh generation, and both three-dimensional and reduced-order computational haemodynamics simulations including incompressible Navier-Stokes and fluid-structure interaction.

Key Features:

• Medical Image Processing: Segmentation of vascular structures from medical images to derive patient-specific vascular geometries.
• Geometric Modeling: Construction of analytic arterial and venous models for detailed hemodynamic representation.
• Mesh Generation: Finite element mesh generation for computational fluid dynamics within vascular geometries.
• Boundary Condition Specification: Design and application of boundary conditions for hemodynamic simulations.
• Simulation Capabilities: Execution of incompressible Navier-Stokes simulations of blood flow and fluid-structure interaction to model blood–vessel wall dynamics.
• Post-processing and Visualization: Computation and visualization of velocity, pressure, and wall shear stress fields.
• Integration with Open-Source Computational Components: Leverages open-source standards for parallel flow computation, geometric solid modeling, data assimilation, and mesh generation.

Scientific Applications:

• Pre-operative Surgical Planning: Patient-specific hemodynamic simulation to inform surgical decision-making and planning.
• Medical Device Design Optimization: Evaluation and optimization of cardiovascular device performance using hemodynamic simulations.

Methodology:

Segmentation of vascular structures from medical images; analytic arterial and venous geometric modeling; finite element mesh generation; three-dimensional and reduced-order incompressible Navier-Stokes solvers; fluid-structure interaction modeling; parallel flow computation, geometric solid modeling, and data assimilation.