CRISPResso2

Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments. CRISPResso2 can be used to analyze genome editing outcomes using cleaving nucleases (e.g. Cas9 or Cpf1) or noncleaving nucleases (e.g. base editors).

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Details

License:
Proprietary
Maturity:
Mature
Cost:
Free of charge (with restrictions)
Tool Type:
command-line tool, web application
Programming Languages:
Python
Added:
5/6/2024
Last Updated:
11/24/2024

Operations

Publications

Clement K, Rees H, Canver MC, Gehrke JM, Farouni R, Hsu JY, Cole MA, Liu DR, Joung JK, Bauer DE, Pinello L. CRISPResso2 provides accurate and rapid genome editing sequence analysis. Nature Biotechnology. 2019;37(3):224-226. doi:10.1038/s41587-019-0032-3. PMID:30809026. PMCID:PMC6533916.

Pinello L, Canver MC, Hoban MD, Orkin SH, Kohn DB, Bauer DE, Yuan G. Analyzing CRISPR genome-editing experiments with CRISPResso. Nature Biotechnology. 2016;34(7):695-697. doi:10.1038/nbt.3583. PMID:27404874. PMCID:PMC5242601.

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