CroP

CroP visualizes time-varying relational biological data to enable analysis and interpretation of temporal patterns such as gene expression dynamics.


Key Features:

  • Dynamic visualization models: Employs dynamic visualization models within flexible panels to represent evolving relational data.
  • Simultaneous dataset analysis: Supports simultaneous upload and analysis of multiple datasets, including large-scale time series data.
  • Clustering and time curve visualization: Provides clustering and time curve visualization to identify groups of data points and temporal patterns, including periodic waves of expression.
  • Integration with public biomedical database for gene annotation: Integrates a public biomedical database to provide gene annotation and contextual information for genetic data.

Scientific Applications:

  • Time-series gene expression analysis: Enables exploration and interpretation of temporal changes in gene expression datasets.
  • Temporal pattern detection in biological networks: Facilitates detection of temporal behaviors and periodic expression waves across relational data.
  • Relational data analysis across biological contexts: Supports analysis of evolving relationships within biological networks using annotated genetic information.

Methodology:

Uses coordinated panel visualization techniques leveraging dynamic models and flexible layouts, combined with clustering and time-curve visualization and integration of public biomedical gene annotation databases.

Topics

Details

Tool Type:
desktop application
Added:
11/14/2019
Last Updated:
12/17/2020

Operations

Publications

Cruz A, Machado P, Arrais JP. CroP—Coordinated Panel visualization for biological networks analysis. Bioinformatics. 2019;36(4):1298-1299. doi:10.1093/bioinformatics/btz688. PMID:31504214.

PMID: 31504214
Funding: - Portuguese Research Agency Fundação para a Ciência e Tecnologia: SFRH/BD/124538/2016 - D4—Deep Drug Discovery and Deployment: CENTRO-01-0145-FEDER-029266

Documentation

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