CryoVR

CryoVR provides an immersive virtual reality environment for practicing cryogenic electron microscopy (cryoEM) experimental procedures to prepare users for acquiring high-resolution structures and studying the dynamics of macromolecular complexes and viruses under near-native conditions.


Key Features:

  • Simulation of cryoEM procedures: Simulates cryoEM experimental procedures including virtual representations of microscopes and sample preparation tools.
  • Assessment and certification: Includes an Exam mode for assessing procedural knowledge and skills and issuing certificates upon successful completion.
  • User feedback and evaluation: Incorporates qualitative evaluations from users with varying cryoEM experience to assess training effectiveness.

Scientific Applications:

  • Operator preparation: Prepares novice users for operating cryoEM apparatus and executing sample-preparation workflows prior to handling physical equipment.
  • Structural biology training: Supports preparation for acquisition and analysis of high-resolution structures of macromolecular complexes and viruses using cryoEM.

Methodology:

Virtual reality simulation of cryoEM experimental procedures with an Exam mode for skill assessment and collection of qualitative user evaluations.

Topics

Details

License:
Other
Cost:
Free of charge
Tool Type:
desktop application
Operating Systems:
Windows
Programming Languages:
C++
Added:
10/9/2022
Last Updated:
11/24/2024

Operations

Publications

Dong J, Li D, Ozcan K, Wan D, Jiang W, Chen Y. Development of <i>CryoVR</i>, a virtual reality training system for hands-on cryoEM operations. Acta Crystallographica Section D Structural Biology. 2022;78(7):903-910. doi:10.1107/s2059798322005654. PMID:35775989. PMCID:PMC9248840.

PMID: 35775989
PMCID: PMC9248840
Funding: - National Institutes of Health: 1R25EY029127-01

Links