CRYPTOMICSDB

CRYPTOMICSDB curates and integrates gene and protein differential expression data to reveal the molecular landscape of cryptococcosis caused by Cryptococcus gattii and Cryptococcus neoformans species complexes.

Key Features:

• Pathogen View: The database contains 19,462 total genes related to pathogen differential expression during infection.
• Host View: The database contains 986,507 total genes related to host differential expression during infection.
• Searchable Metadata: Users can search and filter data by experimental approaches, animal models or cell culture, Cryptococcus species and strain, and specific genes and proteins.
• Dual Perspective Analysis: The database enables separate exploration of pathogen or host molecular information.

Scientific Applications:

• Cryptococcosis Research: Supports health workers and microbiology researchers in understanding the molecular impact of the cryptococcosis infection process.
• Treatment Development: Facilitates molecular understanding that could aid in developing specific treatments and appropriate management strategies for cryptococcosis.

Methodology:

The database was developed by grouping published molecular data on gene and protein differential expression that occurred due to Cryptococcus infection.