cshl_fastx_collapser

cshl_fastx_collapser collapses identical sequences in FASTA files to reduce redundancy and facilitate efficient processing of data from next-generation DNA sequencing (NGS).


Key Features:

  • Sequence Collapsing: Identifies and collapses identical sequences within FASTA files into single representative entries while preserving sequence information.
  • Galaxy Integration: Integrates with the Galaxy Project for execution within Galaxy workflows and platforms.
  • Provenance Tracking: Tracks computational steps and records processing provenance within the Galaxy ecosystem to support reproducibility.

Scientific Applications:

  • Genomics and Transcriptomics: Reduces dataset size in genomics and transcriptomics studies by collapsing identical sequences.
  • Data Reduction: Streamlines large-scale sequence datasets to simplify downstream analyses.
  • Resource Optimization: Decreases computational load and storage requirements for high-throughput sequencing datasets.
  • Improved Downstream Analysis: Emphasizes unique sequences to aid accuracy of downstream bioinformatic analyses.

Methodology:

Parses FASTA files to identify duplicate sequences and collapses them into single entries, with execution and provenance recording performed within the Galaxy platform.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Perl
Added:
12/19/2016
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links

Related Tools

fastx-toolkit
Relation: includedIn