CWDPRNP

CWDPRNP analyzes prion protein (PRNP) gene variability and spatial genetic structure to characterize allele and genotype distributions associated with chronic wasting disease (CWD) in cervid populations.

Key Features:

• PRNP SNP analysis: Examines single nucleotide polymorphisms (SNPs) within the prion protein (PRNP) gene associated with CWD susceptibility.
• Spatial genetic structure analysis: Assesses spatial patterns in genetic data to map distributions of disease-associated alleles and genotypes.
• Integrated analytical framework: Combines analyses of genetic variability and spatial structure to enable simultaneous evaluation of genotype distributions.
• R-based statistical implementation: Implements statistical methods in the R environment for genetic and spatial analyses.

Scientific Applications:

• Disease management: Identifies and monitors frequencies of alleles associated with CWD susceptibility to inform management strategies.
• Ecological research: Enables study of ecological impacts of prion diseases on cervid populations by linking genetic predispositions with spatial distributions.

Methodology:

Statistical analyses implemented in R to process genetic data, analyze PRNP SNPs, and assess spatial genetic structure.